LB13. ICUAW (ICU-acquired weakness)

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The role of inflammation in ICU-acquired weakness

A pilot observational study by Weber-Carstens and colleagues contributes to a mechanistic explanation of the puzzling and complex phenomena of ICU-acquired weakness (ICU-AW). The authors suggest systemic, inflammatory-mediated pathology is the most significant risk factor for ICU-AW. While this finding is somewhat equivocal, it provides important direction for future investigations and illustra...

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ICU-acquired weakness: should medical sovereignty belong to any specialist?

ICU-acquired weakness (ICUAW), including critical illness polyneuropathy, critical illness myopathy, and critical illness polyneuropathy and myopathy, is a frequent disabling disorder in ICU subjects. Research has predominantly been performed by intensivists, whose efforts have permitted the diagnosis of ICUAW early during an ICU stay and understanding of several of the pathophysiological and c...

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ICU-acquired weakness and recovery from critical illness.

Copyright © 2014 Massachusetts Medical Society. W eakness acquired in the intensive care unit (ICU) is caused by many different pathophysiological mechanisms that are not mutually exclusive. This is not surprising, given the diverse diseases that precipitate critical illness, the drugs used during its management, and the consequences of protracted immobility. Nonetheless, conceptualization of t...

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Randomised controlled trial using daily electrical muscle stimulation (EMS) in critically ill patients to prevent intensive care unit (icu) acquired weakness (ICUAW)

Methods The interventional randomized controlled trial included critically ill patients at high risk for ICUAW selected by SOFA score ≥ 9 and onset of critical illness in less than 72 hours. Randomization was administered to EMS group (protocol base physiotherapy and additional EMS) or a physiotherapy group (protocol base physiotherapy). EMStherapy was applied for 20 minutes 7 days/week to 8 bi...

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Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study

INTRODUCTION ICU-acquired weakness is thought to mediate physical impairments in survivors of critical illness, but few studies have investigated this thoroughly. The purpose was to investigate differences in post-ICU mortality and physical functioning between patients with and without ICU-acquired weakness at 6 months after ICU discharge. METHOD ICU patients, mechanically ventilated ≥ 2 days...

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ژورنال

عنوان ژورنال: Clinical Neurophysiology

سال: 2019

ISSN: 1388-2457

DOI: 10.1016/j.clinph.2019.06.068